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Program Schedule
2021 Shock Society Meeting, Portland, Oregon Monday, October 11
5:00 pm–8:00 pm Registration
5:00 pm–8:00 pm Council Meeting (By Invitation Only)
Tuesday, October 12
7:00 am–5:00 pm Registration
7:00 am–8:30 am Shock Editorial Board Meeting (By Invitation Only)
8:30 am–9:00 am Break
9:00 am–11:00 am Plenary Session I
Top Ranked Abstracts and Diversity Winner
Moderators: Marc Jeschke, M.D., Ph.D., FACS, FCCM, FRCS(C)
Sunnybrook Research Institute, Toronto, Ontario
Laurie Kilpatrick, Ph.D.
Temple University School of Medicine, Philadelphia, Pennsylvania
11:00 am–11:20 am Break
11:20 am–1:00 pm Research Panel Discussion
11:20 am–11:40 am Diversity in Science
Arthur Jason Vaught III, M.D.
Johns Hopkins University, Baltimore, Maryland
11:40 am–Noon Gender in Science
Michaela A. West, M.D., Ph.D., FACS
North Memorial Health, Minneapolis, Minnesota
Noon–12:20 pm Updates in Human Ethics in Research
Marie-Carmelle Elie, M.D., FACEP, FCCM, FAAEM, RDMS
University of Florida, Gainesville, Florida
12:20 pm–12:40 pm Updates in Animal Ethics in Research
Basilia Zingarelli, M.D., Ph.D.
Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio
12:40 pm–1:00 pm Q & A
Moderators: Scott Somers, Ph.D.
Bethesda, MD
Xiaoli Zhao, Ph.D.
National Institute of General Medical Sciences, Bethesda, Maryland
1:00 pm–1:40 pm Lunch
1:40 pm–2:40 pm Battles and Successes in the Beginning of Your Career
1:40 pm–2:00 pm K Fundee
Vanessa Nomenelli, M.D., Ph.D.
University of Cincinnati, Cincinnati, Ohio
2:00 pm–2:20 pm R Fundee
Myung S. Park, M.D., M.S.
Mayo Clinic, Rochester, Minnesota
2:20 pm–2:40 pm Q & A
Moderators: Scott Somers, Ph.D.
Bethesda, MD
Xiaoli Zhao, Ph.D.
National Institute of General Medical Sciences, Bethesda, Maryland
2:40 pm–3:00 pm Break
3:00 pm–4:30 pm Parallel Session I
Title: Inflammation—The Good, the Bad, and the Modifiable
Topic: Inflammation
3:00 pm–3:20 pm Modulation of the Immuno-Inflammatory Response by the Cannabinoid System
Jeremie Joffre, Ph.D., M.D.
University of California, San Francisco, San Francisco, California
3:20 pm–3:30 pm Abstract
3:30 pm–3:40 pm Role of Platelets in Inflammation Following Injury
Marc Hanschen
3:40 pm–3:50 pm Abstract
3:50 pm–4:20 pm Sepsis-Associated Adipose Tissue Inflammation
Jennifer Kaplan, M.D., M.S.
Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
4:20 pm–4:30 pm Abstract
Moderators: Judith Hellman, M.D.
University of California, San Francisco, San Francisco, California
Elizabeth J. Kovacs, Ph.D.
University of Colorado Anschutz Medical Campus, Aurora, Colorado
3:00 pm-4:30 pm Parallel Session Il
Title: TBD
Topic: Viruses and COVID
3:00 pm–3:20 pm The Protective and Harmful Effects of Airspace Glycan Shedding in Response to Viral Infection
Eric Schmidt, M.D.
University of Colorado Anschutz Medical Campus, Aurora, Colorado
3:20 pm–3:30 pm Abstract
3:30 pm–3:50 pm Animal Models of COVID
Marcin Osuchowski, DVM, Ph.D.
Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Vienna, Austria
3:50 pm–4:00 pm Abstract
4:00 pm–4:20 pm Immune Endotyping the Host Response to Bacterial and Viral Sepsis in the Era of COVID-19: Making Lemonade When Life Gives You Lemons
Scott Brakenridge, M.D., MSCS
University of Florida, Gainesville, Florida
4:00 pm–4:30 pm Abstract
Moderators: Scott Brakenridge, M.D., MS
University of Florida, Gainesville, Florida
Sarah Yuan, M.D., Ph.D.
University of South Florida, Tampa, Florida
4:30 pm–5:00 pm Break
5:00 pm–6:00 pm Presidential Address
Laurie Kilpatrick, Ph.D.
Temple University School of Medicine, Philadelphia, Pennsylvania
6:30 pm–8:30 pm Poster Session I and Welcome Reception
Wednesday, October 13
7:00 am–5:00 pm Registration
7:00 am–8:30 am Continental Breakfast
7:00 am–8:30 am Pan-Asian Shock Society Presentations
Moderators: Yong-Ming Yao, M.D.
Burns Institute, Beijing, China
Philip A. Efron, M.D., FACS, FCCM
University of Florida, Gainesville, Florida
8:30 am–8:50 am Break
8:50 am–9:20 am Committee Meetings
8:50 am–10:20 am Poster Session Il
10:20 am–10:40 am Break
10:40 am–11:50 am Research Award Recipient Presentations
11:50 am–1:00 pm Lunch
11:50 am–1:00 pm New Investigator Presentations
1:00 pm–1:20 pm Break
1:20 pm–2:50 pm Parallel Session Ill
Title: Myology and Catabolism in Critical Illness
Topic: Myology, Metabolism, Catabolism
1:20 pm–1:40 pm Muscle Wasting as a Major Driver of Sepsis Development
Masao Kaneki, M.D., Ph.D.
Massachusetts General Hospital, Boston, Massachusetts
1:40 pm–1:50 pm Abstract
1:50 pm–2:10 pm The Musculoskeletal Cost of Organ Repair
Prof. Teresa A Zimmers, Ph.D.
Indiana University School of Medicine, Indianapolis, Indiana
2:10 pm–2:20 pm Abstract
2:20 pm–2:40 pm Post-Sepsis Chronic Muscle Weakness in a Novel Preclinical
University of Kentucky, College of Medicine, Lexington, Kentucky
2:40 pm–2:50 pm Abstract
Moderators: Hiroshi Saito, Ph.D.
University of Kentucky, College of Medicine, Lexington, Kentucky
Prof. Teresa A Zimmers, Ph.D.
Indiana University School of Medicine, Indianapolis, Indiana
1:20 pm–2:50 pm Parallel Session IV
Title: New Insights Into Sepsis-Induced Organ Dysfunction—Experimental and Clinical
Topic: Organ-Specific Shock (Not Including Brain)
1:20 pm–1:25 pm Solving the “Mice vs. Women (or Men)” Conundrum—Organ Dysfunction as the Outcome Variable
Feinstein Institute, Halesite, New York
1:25 pm–1:35 pm Abstract
1:35 pm–1:54 pm Molecular Phenotyping for Ards
Pratik Sinha, MBChB, Ph.D.
Washington University School of Medicine, St. Louis, Missouri
1:54 pm–2:04 pm Abstract
2:04 pm–2:23 pm The Pathobiology of Siaki
Daniel Leisman, M.D.
Massachusetts General Hospital, Boston, Massachusetts
2:23 pm–2:33 pm Abstract
2:33 pm–2:50 pm Making Mice More Immunologically Human
Matthew Taylor, M.D.
Feinstein Institute, New Hyde Park, New York
Moderators: Clifford S. Deutschman, M.S., M.D.
Feinstein Institute, Halesite, New York
Jaimar C. Rincon, Ph.D.
University of Florida, Gainesville, Florida
2:50 pm–3:20 pm Break
3:20 pm–3:50 pm Title: TBD
Topic: NIGMS Vision for Future Sepsis Research and/or Biobanking
Xiaoli Zhao, Ph.D.
National Institute of General Medical Sciences, Bethesda, Maryland
3:50 pm–4:00 pm Break
4:00 pm–5:30 pm Parallel Session V
Title: SHOCKing Insights Into Sepsis
Topic: Sepsis
4:00 pm–4:05 pm Introduction to the Session and Framing of the Future of Sepsis
4:05 pm–4:15 pm Focused Presentation of Large Database Analysis of Sepsis Trajectories
Kimberly Sciarretta, Ph.D.
U.S. Department of Health and Human Services, Washington, D.C.
4:15 pm–4:20 pm Reimagining Government-Based New Knowledge Discovery Via an IPA
Kimberly Sciarretta, Ph.D.
U.S. Department of Health and Human Services, Washington, D.C.
4:20 pm–4:35 pm The Key Role of a Data Scientist in Big Data, Al and Ml Drive Inquiry
TBD
4:35 pm–4:50 pm The Role of INKT Cells in Controlling and Modulating the Short- and Long-Term Immune Response in Sepsis
Daithi Heffernan, M.D., AFRCSI
Brown University, Rhode Island Hospital, Providence, Rhode Island
4:50 pm–5:00 pm Panel Discussion
5:00 pm–5:10 pm Abstract
5:10 pm–5:20 pm Abstract
5:20 pm–5:30 pm Abstract
Moderators: Alicia Mohr, M.D., FACS, FCCM
University of Florida, Gainesville, Florida
Lewis J. Kaplan, M.D., FACS, FCCM, FCC
University of Pennsylvania, Philadelphia, Pennsylvania
4:00 pm–5:30 pm Parallel Session Vl
Title: Timing and Cell Type in Trauma
Topic: Trauma
4:00 pm–4:20 pm Trauma Resuscitation Timing Effects on Inflammatory Mediators
Danielle Gruen, Ph.D.
University of Pittsburgh, Pittsburgh, Pennsylvania
4:20 pm–4:30 pm Abstract
4:30 pm–4:50 pm Endothelial Dysfunction and Calcium Channel Signaling After Trauma
Kalev Freeman, M.D., Ph.D.
University of Vermont, Burlington, Vermont
4:50 pm–5:00 pm Abstract
5:00 pm–5:20 pm Hypercoagulability of Trauma: Timing, Transfusion, and Endothelial Crosstalk
Jessica C. Cardenas, Ph.D.
University of Texas, Houston, Texas
5:20 pm–5:30 pm Abstract
Moderators: Mitchell J. Cohen, M.D.
Denver Health, Denver, Colorado
Melanie Scott, M.D., Ph.D.
University of Pittsburgh, Pittsburgh, Pennsylvania
5:30 pm–6:00 pm Break
6:00 pm–8:00 pm Mentoring Reception and New Investigator Award Presentation
Thursday, October 14
7:00 am–5:00 pm Registration
7:00 am–7:30 am Committee Meetings
6:30 am–7:30 am Breakfast
7:30 am–9:00 am Keynote Address: Metabolic and Epigenetic Reprogramming in Trained Immunity
Prof. Mihai G. Netea, Ph.D.
Radboud University Medical Center, Nijmegen, The Netherlands
Moderator: Philip A. Efron, M.D., FACS, FCCM
University of Florida, Gainesville, Florida
9:00 am–9:20 am Break
9:20 am–10:50 am European Shock Society Presentations
Moderators: Evangelos J. Giamarellos-Bourboulis, M.D., Ph.D.
University of Athens, Athens, Greece
Philip A. Efron, M.D., FACS, FCCM
University of Florida, Gainesville, Florida
10:50 am–11:10 am Break
11:10 am–12:10 pm Shock Business Meeting
12:10 pm– 1:10 pm Lunch
12:10 pm– 1:10 pm Parallel Session Vll
Oral Presentations by and for Young Investigators
12:10 pm–1:10 pm Parallel Session Vlll
Technology Session
Title: Integration of In Silico, In Vitro and In Vivo Models for Translational Studies
Carrie German, Ph.D.
CFD Research Corporation, Stillwater, Oklahoma
Moderator: Laurie Kilpatrick, Ph.D.
Temple University School of Medicine, Philadelphia, Pennsylvania
1:10 pm–1:30 pm Break
1:30 pm–3:00 pm Parallel Session lX
Title: Impact of Military Discoveries on Civilian Practice
Topic: Military
1:30 pm–1:35 pm Introduction
Rosemary A. Kozar, M.D., Ph.D.
University of Maryland, Baltimore, Maryland
1:35 pm–1:55 pm Impact of Military Practice on Civilian Pre-Hospital Use of Blood Products
Jason L. Sperry, M.D., MPH
University of Pittsburgh, Pittsburgh, Pennsylvania
1:55 pm–2:05 pm Abstract
2:05 pm–2:25 pm Plasma for Burn Resuscitation: Back to the Future
Leopoldo Carlos Cancio, M.D.
U.S. Army Institute of Surgical Research, San Antonio, Texas
2:25 pm–2:35 pm Abstract
2:35 pm–3:00 pm Update on Dried Plasma for Emergency and Prehospital Use in Trauma
Anthony E. Pusateri, Ph.D.
U.S. Army Institute of Surgical Research, San Antonio, Texas
Moderators: Irshad Chaudry, Ph.D.
University of Alabama at Birmingham, Birmingham, Alabama
Rosemary A. Kozar, M.D., Ph.D.
University of Maryland, Baltimore, Maryland
1:30 pm–3:00 pm Parallel Session X
Title: A Fate Worse Than Death? Neurocognitive Sequelae of Critical Illness and Shock
Topic: Neurocognitive Sequelae of Critical Illness And Shock
1:30 pm–1:50 pm Challenges to Survivorship After Shock
Pratik Pandharipande, M.D., MSCI
Vanderbilt University Medical Center, Nashville, Tennessee
1:50 pm–2:00 pm Abstract
2:00 pm–2:20 pm Biomarkers and Cognition After Sepsis
Marie-Carmelle Elie, M.D., FACEP, FCCM, FAAEM, RDMS
University of Florida, Gainesville, Florida
2:20 pm–2:30 pm Abstract
2:30 pm–2:50 pm Neuroimaging and EEG Correlates of Cognitive Decline
Shawniqua Williams Roberson, MEng, MD
Vanderbilt University Medical Center, Department of Neurology
2:50 pm–3:00 pm Abstract
Moderators: Marie-Carmelle Elie, M.D., FACEP, FCCM, FAAEM, RDMS
University of Florida, Gainesville, Florida
Pratik Pandharipande, M.D., MSCI
Vanderbilt University Medical Center, Nashville, Tennessee
3:00 pm–3:30 pm Break
3:30 pm–4:00 pm Biotech Startups
John Younger, M.D.
University City Science Center, Philadelphia, Pennsylvania
4:00 pm– 4:30 pm International Biological Patents
Frank Christopher Eisenschenk, Ph.D., J.D.
Saliwanchik, Lloyd & Eisenschenk, Gainesville, Florida
5:15 pm–6:45 pm Poster Session Ill
5:15 pm–6:45 pm Committee Meetings
Friday October 15
7:00 am–3:30 pm Registration
7:00 am–8:30 am Continental Breakfast
7:00 am–8:30 am Poster Session IV
8:30 am–9:30 am Latin American Shock Society Presentations
Moderator: Prof. Reinaldo Salomao
Universidade Federal de Sao Paulo/Escola Paulista de Medicina, Sao Paulo, Brazil
9:30 am–9:50 am Break
9:50 am–11:20 am Parallel Session IX
Title: Understanding Immune Function After Severe Burns: From Bench to Bedside
Topic: Burn
9:00 am–9:15 am Clinical Perspective
Ronald G Tompkins, M.D., ScD
Harvard-Affiliated Hospitals, Boston, Massachusetts
9:15 am–9:30 am Pathophysiology and Immune Function
Martin Schwacha, Ph.D.
University of Texas Health Science Center, San Antonio, Texas
9:30 am–9:40 am Abstract
9:40 am–9:55 am Hepatic Signaling and the Inflammatory Response After Burn
Darren Boehning, Ph.D.
Cooper Medical School of Rowan University, Camden, New Jersey
9:55 am–10:10 am Burn Injury in the Aging Patient—The Role of Liver Necroptosis
Juan-Pablo Idrovo, M.D.
University of Colorado, Aurora, Colorado
10:10 am–10:20 am Abstract
10:20 am–10:40 am Future Outlook, Novel Strategies
Shibani Pati, M.D., Ph.D.
University of California San Francisco, San Francisco, California
10:40 am–10:50 am Abstract
Moderators: Kathleen S. Romanowski, M.D., MAS
UC Davis Health, Sacramento, California
Kevin K. Chung, M.D., FCCM, FACP
Uniformed Services University, Bethesda, Maryland
9:50am–11:20 am Parallel Session X
Title: The Central Role of the Gut Microbiome in Sepsis and Critical Illness
Topic: Microbiome
9:00 am–9:20 am Dietary Influences on the Emergence of a Gut Resistome During Critical Illness: Implications for Late Onset Sepsis
Robert Keskey, M.D.
University of Chicago Department of Surgery, Chicago, Illinois
9:20 am–9:30 am Abstract
9:30 am–9:40 am Are We Properly Nourishing Our Microbiome During Critical Illness When We Feed Sterile, Chemically Defined Liquid Food?
Victoria M. Gershuni, M.D., MSGM
University of Pennsylvania, Philadelphia, Pennsylvania
9:40 am–9:50 am Abstract
9:50 am–10:10 am Microbiome Maintenance Therapy and Fecal Transplant During Critical Illness: Are We Ready for This?
Jennifer DeFazio, M.D.
Columbia University, New York, New York
10:10 am–10:20 am Abstract
10:20 am–10:40 am The Gut Microbiome Drives the Immune Phenotype During Sepsis and Influences Survival
Nathan John Klingensmith, M.D.
Emory University Hospital, Atlanta, Georgia
10:40 am–11:20 am Q&A
Moderators: John C. Alverdy, M.D.
The University of Chicago, Chicago, Illinois
Craig Coopersmith, M.D.
Emory University, Atlanta, Georgia
11:20 pm–Noon Lunch
Noon–1:30 pm Parallel Session XI
Title: Advances in Single-Cell Technologies in Shock Research
Topic: Novel Technology for the Research of Shock
Noon–12:20 pm Single-Cell Technologies in Detecting Gene Expression Change at Epigenetics, Transcriptomics, and Translation Levels
Meihong Deng, M.D.
The Ohio State University, Columbus, Ohio
12:20 pm–12:30 pm Abstract
12:30 pm–12:50 pm Single Cell RNA Sequencing in Human Health and Disease
Matthew J. Delano, M.D.
University of Michigan, Ann Arbor, Michigan
12:50 pm–1:00 pm Abstract
1:00 pm–1:20 pm Mass Cytometry (CyTOF) for Trauma and Sepsis Immunology Research
James A. Lederer, Ph.D.
Brigham and Women's Hospital, Boston, Massachusetts
1:20 pm–1:30 pm Abstract
Moderators: Matthew J. Delano, M.D.
University of Michigan, Ann Arbor, Michigan
Meihong Deng, M.D.
The Ohio State University, Columbus, Ohio
Noon–1:30 pm Parallel Session XII
Title: Outcomes and Endotypes in Shock and Critical Illness
Topic: Outcomes and Endotypes
Noon–12:20 pm Endotypes, Phenotypes, and Outcomes in Critically Illness
Joseph Cuschieri, M.D.
Harborview Medical Center, Seattle, Washington
12:20 pm–12:30 pm Abstract
12:30 pm–12:50 pm Multi-Omic Strategies to Identify Endotypes After Trauma
Timothy R. Billiar, M.D.
University of Pittsburgh, Pittsburgh, Pennsylvania
12:50 pm–1:00 pm Abstract
1:00 pm–1:20 pm Precision Medicine in Critical Illness—How Do We Get There?
Sachin Yende, M.D., M.S.
University of Pittsburgh, Pittsburgh, Pennsylvani
1:20 pm–1:30 pm Abstract
Moderators: Joseph Cuschieri, M.D.
Harborview Medical Center, Seattle, Washington
Sachin Yende, M.D., M.S.
University of Pittsburgh, Pittsburgh, Pennsylvania
1:30 pm–1:50 pm Break
1:50 pm–3:20 pm Parallel Session XIII
Title: Precision Medicine in the Management of Trauma Induced Coagulopathy
Topic: Hemorrhage and Blood
1:50 pm–1:55 pm Introduction: “Trauma Induced Coagulopathy”
Ernest E. Moore, M.D.
University of Colorado Denver, Denver, Colorado
1:55 pm–2:10 pm Clotting Factors
Martin A. Schreiber, M.D., FACS, FCC
Oregon Health & Science University, Portland, Oregon
2:10 pm–2:20 pm Abstract
2:20 pm–2:35 pm Platelets
Dr. Lucy Zumwinkle Kornblith, M.D.
University of California San Francisco, San Francisco, California
2:35 pm–2:45 pm Abstract
2:45 pm–3:05 pm Fibrinogen
Matthew D. Neal, M.D.
University of Pittsburgh, Pittsburgh, Pennsylvania
3:05 pm–3:15 pm Abstract
3:15 pm–3:30 pm Tranexamic Acid
Hunter Moore, M.D., Ph.D.
University of Colorado Denver, Denver, Colorado
Moderators: Ernest E. Moore, M.D.
University of Colorado Denver, Denver, Colorado
Basilla Zingarelli, M.D., Ph.D.
Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
1:50 pm–3:20 pm Topic: Vascular and Epithelium XIV
Moderators: Wendy Walker, Ph.D.
Texas Tech University Health Center, El Paso, Texas
Jonathan J. Morrison, MB, ChB, Ph.D., FRCS
University of Maryland, Baltimore, Maryland
3:20 pm–3:30 pm Break
3:30 pm–4:30 pm Parallel Session XV
Epigenetics and Exosomes in Shock
3:30 pm–3:50 pm Epigenetics in Shock
Michael Kladde, Ph.D.
University of Florida, Gainesville, Florida
3:50 pm–4:00 pm Abstract
4:00 pm–4:20 pm Exosomes in Shock
Thomas C. Foster, Ph.D.
University of Florida, Gainesville, Florida
4:20 pm–4:30 pm Abstract
Moderators: Thomas C. Foster, Ph.D.
University of Florida, Gainesville, Florida
Michael Kladde, Ph.D
University of Florida, Gainesville, Florida
3:30 pm–4:30 pm Parallel Session XVI
The Application of Artificial Intelligence to Shock
5:30 pm–8:30 pm Dinner
Scientific Achievement and Distinguished Service Awards and Travel Awards Ceremony
Speakers: Scott Somers, Ph.D.
Bethesda, MD
Irshad Chaudry, Ph.D.
The University of Alabama at Birmingham, Birmingham, Alabama
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