Current Working Schedule for 2025 Conference: View PDF


Saturday May 31, 2025
8:00 AM- 12:00 PM Executive Committee Meetings
12:00 PM - 1:00 PM Lunch Break (on your own)
1:00 PM - 1:05 PM General Session Welcome and Introduction: Philip Efron MD, University of Florida, President, Shock Society (2024-2025)
1:05 PM - 2:30 PM Plenary Session 1:  Prehospital Trauma Resuscitation and Results of Recent Clinical Trials
Session Chairs:
          Rosemary Kozar, MD, PhD, University of Maryland
          Manabu Kinoshita, MD, PhD, National Defense Medical College, Japan
1:05 PM - 1:23 PM Invited Presentation: Recent Clinical Trials of Blood Products for Prehospital Acute Trauma Resuscitation - Jason Sperry, MD, MPH, University of Pittsburgh
1:23 PM - 1:41 PM Invited Presentation: Capillary Perfusing Targeting Oxygen Transfer in Prehospital Shock Resuscitation, Martin Mangino, PhD, Virginia Commonwealth University
1:41 PM - 2:00 PM Invited Presentation: Role of Coagulation Factor Concentrates for Trauma Resuscitation, Martin Schreiber, MD, Oregon Health & Science University
2:00 PM - 2:10 PM Abstract Presentation: DNAse Treatment Attenuates Serum Cell Free DNA After Polytrauma and Resuscitation (4285452)
2:10 PM - 2:20 PM Abstract Presentation: Prehospital Administration of 25% Albumin or Plasma Maintains Mitochondrial Respiratory Capacity in Rats With Decompensated Hemorrhagic Shock (4291597)
2:20 PM - 2:30 PM Abstract Presentation: Prehospital Lyophilized Cryoprecipitate Improves Coagulation Function and Blood Pressure Compared to Crystalloid in a Nonhuman Primate Hemorrhage Model (4291634)
2:30 PM - 3:30 PM Top Rated Abstracts
Session Chairs:
          Philip Efron, MD, University of Florida
          Haichao Wang, PhD, The Feinstein Institutes for Medical Research, New York
2:30 PM - 2:42 PM Abstract Presentation: Mitigation of Acute Kidney Injury by Canaglifozin is Associated with Increased Apoptosis and Mitochondrial Fission in a Porcine Model of Hemorrhagic Shock, Zaria Killingsworth, BA, Uniformed Services University of Health Sciences, Bethesda, Maryland
2:42 PM - 2:54 PM Abstract Presentation: Proteomic Analysis Reveals a Potential Severity Threshold for Gasmerdin D Activation Following Hemorrhagic Shock and Tissue Trauma,  Aileen Ritter, Dr Med, University of Pittsburgh
2:54 PM - 3:06 PM Abstract Presentation: Distinct Metabolic Signatures in Pediatric Sepsis: Insights into Pathophysiology and Biomarker Discovery, Nora Wolff, MD, Children's National Hospital, Washington DC
3:06 PM - 3:18 PM Abstract Presentation: Red-shifted Optogenic Stimulation of the Inflammatory Reflex Regulates Inflammation in Endotoxemia, Kicheon Park, PhD, Northwell University, New York
3:18 PM - 3:30 PM Abstract Presentation: Increases in Monocyte Distribution Width Portend Spesis in Febrile Children Presenting to the Emergency Department, Lael Yonker, MD, MGH Harvard University, Cambridge
3:30 PM - 4:00 PM Refreshment Break
4:00 PM - 5:30 PM Plenary Session 2: Compare and Contrast - Coagulopathy of Trauma, Burns, Sepsis, TBI
Session Chairs:
          Hunter Moore, MD, PhD, Advent Health, Denver, Colorado
          Peter K. Moore, MD, University of Colorado Anschutz Medical Campus
4:00 PM - 4:20 PM Invited Presentation: Extracellular Vesicles in Coagulopathy, Basilia Zingerelli, MD, PhD, Cincinnati Children's Hospital Medical Center
4:20 PM - 4:40 PM Invited Presentation: Role of Dysregulated Fibrinolysis in Multiple Disorders, E.E. Moore, MD, University of Colorado
4:40 PM - 5:00 PM Invited Presentation: Pediatric Coagulopathy of Trauma and Sepsis, Allison Nair, MD, University of California San Francisco
5:00 PM - 5:10 PM Abstract Presentation: Caspase-11 Inhibition Decreases Clot Formation and Increases Organ Damage Following Polytrauma (4282568)
5:10 PM - 5:20 PM Abstract Presentation: Validation of Microfluidic Assessment of Hemostasis in Trauma-Induced Coagulopathy Using Existing Assays (4294558)
5:20 PM - 5: 30 PM Abstract Presentation: Dimethyl Sulfoxide Reduces Glycocalyx Shedding and Coagulopathy in a Rat Hemorrhage-Resuscitation Model (4294560)
5:30 PM - 6:30 PM Presidential Address
Presented By: Haichao Wang, Ph.D., The Feinstein Institutes for Medical Research, New York, President, Shock Society (2025-2026)
Introduction: Philip Efron, MD, University of Florida, President, Shock Society (2024-2025)
6:30 PM - 7:30 PM Welcome Reception
7:30 PM - 9:00 PM Mentoring Workshop
Session Chairs:
          Kalev Freeman, MD, PhD, University of Vermont
          Marcin Osuchowski, DVM, PhD, Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Vienna, Austria 


Sunday, June 1, 2025
7:30 AM - 9:00 AM Poster Session 1 (Computational Sciences/Artificial Intelligence/Big Data/Precision Medicine; Immunology/Inflammation; Military, Disaster, and Prehospital Medicine; Neuro-Immune Crosstalk; Sepsis)
7:30 AM - 9:00 AM Breakfast
9:00 AM - 10:40 AM Plenary Session 3: Military, Disaster and Austere Environments - Novel Blood Products and Resuscitative Adjuncts
Session Chairs:
          CAPT Jacob Glaser, MD, US Navy Reserve
          COL Martin Schreiber, MD, US Army Reserve
9:00 AM - 9:20 AM Invited Presentation: White Blood Cell Membrane-Coated Nanoparticles: Recent Development and Medical Applications, Liangfang Zhang, PhD,  University of California San Diego
9:20 AM - 9:40 AM Invited Presentation: Oxygen Carriers and Artificial Blood - Where are We?, Allan Doctor, MD, University of Maryland School of Medicine
9:40 AM - 10:00 AM Invited Presentation: Tranexamic Acid in Acute Trauma – Beyond Hemostasis, Joseph F. Rappold, MD , CAPT, US Navy (Retired), Maine Medical Center, Tufts University School of Medicine
10:00 AM - 10:20 AM Invited Presentation:  Blood Requirements for Military and Disaster Scenarios, Noah M. Igra, MD, Maimonides Medical Center, Brooklyn, New York
10:20 AM - 10:30 AM Abstract Presentation: Effects of Chemokine (C-C Motif) Receptor 1 Antagonist BX471 During Resuscitation from Hemorrhagic Shock (4283146)
10:30 AM - 10:40 AM Abstract Presentation: Hemorrhagic Shock Impairs Oxygen Diffusion Independent of Altered Oxygen Delivery (4291518) 
10:30 AM - 11:00 AM Refreshment Break
11:00 AM - 12:00 PM                                                                                     Keynote Presentation: Decoding the Resolution Response in Inflammation Uncovers Novel Pro-Resolving Mediators that Reduce Infectious Inflammation, Pain and Protect Organs
Presented By: Professor Charles N. Serhan, PhD, DSc, Simon Gelman Professor of Anaesthesia (Biochemistry and Molecular Pharmacology), Harvard Medical School, Cambridge, Massachusetts
Introduction: Anthony E. Pusateri, PhD, 59th Medical Wing, Lackland Air Force Base, San Antonio, Texas
12:00 PM - 1:00 PM Box Lunch
12:00 PM - 1:00 PM Presentations by and for Young Investigators
Session Chairs:
          Matthew Alves, University of Florida
          Kartik Rajagopalan, MD, PhD, UT Southwestern Medical Center, Dallas, Texas
12:00 PM - 12:12 PM Abstract Presentation: Screening for Sepsis: Novel Use of a Clinically-Validated Glycosaminoglycan Assay Distinguishes Septic Shock from Control Patients (4268306) 
12:12 PM - 12:24 PM Abstract Presentation: EV-Mediated Immunomodulation Attenuates Sepsis-Induced Acute Lung Injury (4281037)
12:24 PM - 12:36 PM Abstract Presentation: Peri-Injury Monocyte Depletion Alters Long-Term Gene Expression Within Microglia After TBI (4292199) 
12:36 PM - 12:48 PM Abstract Presentation: Snooze or Lose: Sleep Interruption Exacerbates Sepsis in Mice, Via a Short-Lived, TLR2-Dependent Mechanism (4293257) 
12:48 PM - 1:00 PM Abstract Presentation: Early Elevation in MDSC Counts in Severe Trauma Patients Not Associated With Clinical Outcomes (4294209) 
1:00 PM - 2:00 PM State of the Journal - Most Downloaded Papers
Session Chairs:
          Daniel Remick, MD, Boston University, Editor in Chief of the SHOCK Journal
          Julia Bohannon, PhD, Vanderbilt University, Tennessee
1:00 PM - 1:20 PM Shock Journal Update 2025, Daniel Remick, M.D. Editor-in-Chief, Shock, Boston University Chobanian and Avedisian School of Medicine
1:20 PM - 1:32 PM Most Downloaded Paper Presentation: Inhibition of Integrin VLA-3 and Tetraspanin CD151 Protects Against Neutrophil-mediated Endothelial Damage, Jonathan Reichner, PhD, Department of Surgery, Rhode Island Hospital and Brown University
1:32 PM - 1:44 PM Most Downloaded Paper Presentation: Applying Transcriptomics and AI to the Bedside, a Journey in Sepsis Dynamics, Asrar Rashid, MBChB, PhD, MBA, Department Pediatric Intensive Care and Health Informatics and Digitisation, NMC Royal Hospital, Khalifa City, Abu Dhabi, United Arab Emirates
1:44 PM - 1:56 PM Most Downloaded Paper Presentation: Angiotensin II in the Treatment of Distributive Shock: a Systematic Review and Meta-analysis, Eleni Xourgia, MD, MSc, University Clinic for Emergency Medicine, Inselspital, University of Bern, Bern, Switzerland
2:00 PM - 3:00 PM New Investigator Competition
Session Chairs:
          Lauren Moffatt, PhD, Medstar Health Research Institute, Washington, DC
          Monowar Aziz, PhD, Feinstein Institutes for Medical Research, Northwell Health
2:00 PM - 2:12 PM Abstract Presentation: Spices to Combat Sepsis - Curcumin Piperin Combination Increases Survival and Modulates Immune Response in Two-Hit Trauma Model (4289476)
2:12 PM - 2:24 PM Abstract Presentation: Microglia Depletion Attenuates Immune Cell Chemotaxis After Traumatic Brain Injury in Aged Mice (4291226) 
2:24 PM - 2:36 PM Abstract Presentation: Reinforcement Learning-Guided Resuscitation: Comparing AI-Derived Strategies to Observed ICU Practice (4291692) 
2:36 PM - 2:48 PM Abstract Presentation: Can the Initiation M1/M2 Macrophages Ratio Predict the Long-Term Cognitive Function in Older Sepsis Survivors? (4292009) 
2:48 PM - 3:00 PM Abstract Presentation: Targeted Hepatic MCJ Inhibition Mitigates Post-Surgical Liver Injury and Neuroinflammation in Aged Mice (4294445) 
3:00 PM - 3:30 PM Refreshment Break
3:30 PM - 4:30 PM Research Award Presentations
Session Chairs:
          Lauren Moffatt, PhD, Medstar Health Research Institute, Washington, DC
          Monowar Aziz, PhD, Feinstein Institutes for Medical Research, Northwell Health
3:30 PM - 3:45 PM Japan Shock Society Award Presentation: Life/working Styles of Women Surgeons in Japan and the World, Kumiko Sekiguchi, MD, Nippon Medical School Musashikosugi Hospital, Kanagawa, Japan
3:45 PM - 4:00 PM Japan Shock Society Award Presentation: Persistent Inflammation, Immuno-suppression and Catabolism Syndrome, Dr. Azusa Kato, Japan
4:00 PM - 4:15 PM Research Investigator Award Presentation: Novel Role of Lactate in MDSC-mediated Immunosuppression in Sepsis, Min Fan, MD, PhD, East Tennessee State University
4:15 PM - 4:30 PM Faculty Research Award Presentation: Macrophage-Derived Factor XIII-A: Roles in Inflammation and Repair after Acute Lung Injury, Peter K. Moore, MD, University of Colorado
4:30 PM - 6:30 PM Plenary Session 4: Burn Resuscitation
Session Chairs:
          Jeffrey Shupp, MD, Georgetown University, Maryland and Medstar Health, Washington, DC
          Julia Bohannon, PhD, Vanderbilt University, Tennessee
4:30 PM - 4:48 PM Invited Presentation: Contemporary Understanding of the Systemic Response to Burn Injury: What to Know to Improve Resuscitation Strategies, Vanessa Nomellini, MD, PhD, University of Texas Southwestern Medical Center
4:48 PM - 5:06 PM Invited Presentation: Early FFP Resuscitation in Acute Burns: Experience, Efficacy, and Safety, Arek Wiktor, MD, University of Colorado
5:06 PM - 5:24 PM Invited Presentation: Burn Induced Endothelial and Immune Dysfunction: Looking for Potential Therapies, John Kubasiak, MD, Loyola University of Chicago
5:24 PM - 5:42 PM Invited Presentation: Bundles of Joy? The Function of Extracellular Vesicles After Burn Injury, Robert Maile, PhD, University of Florida
5:42 PM - 6:00 PM Invited Presentation: Coagulation Homeostasis After Burn Injury and Plasma Inclusive Resuscitation: The First 48 Hours, Maria Christina Bravo, PhD, University of Vermont
6:00 PM - 6:10 PM Abstract Presentation: Burns Accelerate Biological Aging and Increase the Epigenetic Risk of Frailty and Mortality (4291666) 
6:10 PM - 6:20 PM Abstract Presentation: Burn Patients with Hemoglobin Levels >6.5 g/dL are at Notable Risk for Adverse Events After Asministration of Blood Transfusion - an Analysis with Real World Data (4292255) 
6:20 PM - 6:30 PM Abstract Presentation: Rapamycin Enhances Trained Immunity and Improves Mortality in a Murine Model of Burn Trauma (4294147)
6:30 PM - 8:00 PM Demystifying the NIH Application Process
Session Chair:
          Craig Coopersmith, MD, Emory University School of Medicine, Atlanta, GA
6:30 PM - 6:50 PM Invited Presentation: Writing the Research Plan, Myung S. Park, MD, MS, Rochester, Minnesota
6:50 PM - 7:10 PM Invited Presentation: Every Part of the Grant That is Not the Research Plan, Melanie Scott, MD, PhD, University of Pittsburgh, Pennsylvania
7:10 PM - 7:30 PM Invited Presentation: What Happens in the Room – How Does the Grant Review Process Work at Study Section, Jennifer Kaplan, MD, MS, Cincinnati Children's Hospital, Cincinnati, Ohio
7:30 PM - 7:50 PM Invited Presentation: Responding to Summary Statement, Craig Coopersmith, MD, Emory University School of Medicine, Atlanta, Georgia
7:50 PM - 8:00 PM Discussion


Monday, June 2, 2025
6:00 AM - 7:30 AM Fun Run
Event Chairs:
          Wendy Walker, PhD, Mercer University, Georgia
          Elisabetta Liverani, PhD, North Dakota State University
7:30 AM - 9:00 AM Poster Session 2 (Burn Injuries/Heat Stroke; Sepsis; Traumatic Brain Injury and Neuro-Inflammation; Treatments; Vascular Biology/Endothelium/Coagulation)
7:30 AM - 9:00 AM Breakfast
9:00 AM - 10:30 AM Parallel Session 1a: Systems Biology, Computational and AI Approaches to Trauma, Burns and Sepsis Research
Session Chairs:
          Mitchell J. Cohen, MD, University of Colorado
          Rishikesan Kamaleswaran, PhD, Duke University, North Carolina
9:00 AM - 9:20 AM Invited Presentation: Plasma Omics Reflect and Predict Trauma Patient Trajectories and Outcomes, Christopher Erickson, PhD, University of Colorado 
9:20 AM - 9:40 AM Invited Presentation: Controlling Coagulation: Towards Automated Coagulation Control, Amor Menzes, PhD, University of Florida
9:40 AM - 10:00 AM Invited Presentation: Cosmic Stress: What Spaceflight Teaches Us About Mitochondrial Breakdown, Shock, and Injury Response, Afshin Beheshti, PhD, University of Pittsburgh
10:00 AM - 10:10 AM Abstract Presentation: Trajectory Analysis Reveals Dampened Serum CCL17 in Acute Respiratory Distress Syndrome Development Following Traumatic Injury or Surgery (4279666) 
10:10 AM - 10:20 AM Abstract Presentation: Single Cell Transcriptomics Reveals Dysfunction and Hypometabolic CXCR4HI IL7RLO Effector CD8 T Cells that are Unique to Human Critical Illness (4291103) 
10:20 AM - 10:30 AM Abstract Presentation: Decreased Whole-Body Mitochondrial Energy Metabolism Identified by Metabolomics and Transcriptomic Analyses in Long-Term Sepsis Survivors (4294595) 
9:00 AM - 10:30 AM Parallel Session 1b: The Gut in Traumatic Hemorrhage, Burn, TBI, and Sepsis
Session Chairs:
          Mashkoor A. Choudhry, Ph.D., Loyola University of Chicago
          Steven J. Schwulst, MD, Northwestern University, Chicago, Illinois
9:00 AM - 9:20 AM Invited Presentation: Gut-Brain Axis after Burn Injury, Elizabeth J. Kovacs, PhD, University of Colorado Denver Anschutz Medical Campus
9:20 AM - 9:40 AM Invited Presentation: microRNA at the Intersection of Microbiome and Gut Homeostasis Following Alcohol and Burn Injury, Mashkoor A. Choudhry, Ph.D., Loyola University of Chicago
9:40 AM - 10:00 AM Invited Presentation: Gut-Brain Axis in TBI, Steven J. Schwulst, MD, Northwestern University, Chicago, Illinois
10:00 AM - 10:10 AM Abstract Presentation: A Multi-Omics Approach Exploring the Gut-Liver Axis Following Combined Radiation Exposure and Burn Injury in a Sinclair Minipig Model (4275784)
10:10 AM - 10:20 AM Abstract Presentation: Gut Microbiota Modulation Restores Immunosuppressive Cells and IgA Secretion in a Gut Microbiota Depletion Model (4282324)
10:20 AM - 10:30 AM Abstract Presentation: Fecal Microbiota Transfer with Stool from Human IBD Patients Results in Neuroinflammation and Anxiety-Like Behavior In Mice (4285959) 
10:30 AM - 11:00 AM Refreshment Break
11:00 AM - 12:30 PM Parallel Session 2a: Platelets in Trauma and Sepsis
Session Chairs:
          Lucy Kornblith, MD, University of California San Francisco
          Elisabetta Liverani, PhD, North Dakota State University
11:00 AM - 11:20 AM Invited Presentation: Post-injury Platelet Biology, Lucy Kornblith, MD, University of California San Francisco
11:20 AM - 11:40 AM Invited Presentation: Cold-stored Platelets in Trauma Transfusion, Matthew D. Neal, MD, Universtiy of Pittsburgh, Pennsylvania
11:40 AM - 12:00 PM Invited Presentation: Sex Differences in Platelet Function During Sepsis, Elisabetta Liverani, PhD, North Dakota State University
12:00 PM - 12:10 PM Abstract Presentation: Evaluation of Stored Platelet Resuscitation Using a Microfluidic Bleeding Chip (4285997)
12:10 PM - 12:20 PM Abstract Presentation: Utilizing Static and Flow Assays to Assess Safety of Synthetic Platelets Ex Vivo (4291821)
12:20 PM - 12:30 PM Abstract Presentation: Extreme Changes in Platelet Aggregation with NEFA and Extracellular ATP Scavenging (4291902)
11:00 AM - 12:30 PM Parallel Session 2b: Novel Hypotheses, Models and Approaches in Shock Research
Session Chairs:
          Vanessa Nomellini, MD, PhD, UT Southwestern Medical Center, Dallas, Texas
          Marlene Starr, PhD, University of Kentucky
11:00 AM - 11:20 AM Invited Presentation: Getting with the Times: Moving from Rodents to Humans or Large Animal Models, Marlene Starr, PhD, University of Kentucky
11:20 AM - 11:40 AM Invited Presentation: Nonhuman Primate Models for the Study of Human-derived Blood Products in Hemorrhagic Shock and Trauma, Clifford G. Morgan, PhD, Naval Medical Research Unit San Antonio, JBSA Fort Sam Houston, Texas
11:40 AM - 12:00 PM Invited Presentation: Normothermic Regional Perfusion in Organ Donors to Study the Effects of Coagulation on Circulatory Arrest and Post Reperfusion on Abdominal Organs, Hunter Moore, MD, PhD, Advent Health, Denver, Colorado
12:00 PM - 12:10 PM Abstract Presentation: Development and Validation of a Novel Lapine Model of Acute Trauma-Induced Coagulopathy (TIC) (4288364)
12:10 PM - 12:20 PM Abstract Presentation: A Novel Multiple DAMPS Scavenger Ameliorates Lethal Sepsis (4288453) 
12:20 PM - 12:30 PM Abstract Presentation: Free Oligosaccharides Reveal Organ-Specific Endoplasmic Reticulum Stress in Polytrauma (4294444) 
12:30 PM - 1:30 PM Shock Society Meeting of Members
1:30 PM - 5:00 PM Free Afternoon/Committee Meetings


Tuesday, June 3, 2025
7:30 AM - 9:00 AM Poster Session 3 (Acute Lung Injury; Hemorrhagic Shock, Resuscitation and Transfusion; Novel Technologies and Approaches to Study Shock Pathophysiology, Outcomes and Treatments; Trauma; Other)
7:30 AM - 9:00 AM Breakfast
9:00 AM - 10:30 AM Parallel Session 3a: Neuroendocrine-Immune Axis in Shock and Sepsis
Session Chairs:
          Judith Hellman, MD, University of California San Francisco
          Kartik Rajagopalan, MD, PhD, UT Southwestern Medical Center, Dallas, Texas
9:00 AM - 9:20 AM Invited Presentation: Modulation of Peripheral Inflammation by Endovanilloid and Endocannabinoids - CNS - Mediated Anti-inflammatory Effects, Judith Hellman, MD, University of California San Francisco
9:20 AM - 9:40 AM Invited Presentation: Sepsis-Associated Brain Injury, Raj Aneja MD, Division of Pediatric Critical Care Medicine and Safar Center for Resuscitation Research, UPMC Children’s Hospital of Pittsburgh
9:40 AM - 10:00 AM Invited Presentation: (Title to be confirmed), Clifford S. Deutschman, MS, MD, Hofstra-Northwell School of Medicine and Feinstein Institutes for Medical Research, Manhasset, New York
10:00 AM - 10:10 AM Abstract Presentation: Nociceptor Alpha 7 Nicotinic Acetylecholine Receptor Activation Blunts Nuclear HMGB1 Release, Which Attenuates Inflammation (4283176)
10:10 AM - 10:20 AM Abstract Presentation: Immunoregulation by Sympathetic (Splanchnic) Nerves (4292375)
10:20 AM - 10:30 AM Abstract Presentation: Neuromodulation of Celiac-Superior Mesenteric Ganglion Complex Using Focused Ultrasound and Optogenetics Regulates Inflammation (4293141)
9:00 AM - 10:30 AM Parallel Session 3b: Phenotypes, Endotypes and Precision Medicine
Session Chairs:
          Scott C. Brakenridge, MD, Universtity of Washington
          Rishikesan Kamaleswaran, PhD, Duke University, North Carolina
9:00 AM - 9:20 AM Invited Presentation: Omics Bioinformatics Approaches, Douglas Brubaker, PhD, Case Western Reserve University, Cleveland, Ohio
9:20 AM - 9:40 AM Invited Presentation: Use of In Silico Models to Identify FDA Approved Therapeutics to Target Specific Neutrophil Phenotypes in Sepsis - a Precision Medicine Approach, Laurie Kilpatrick, PhD, Temple University, Philadelphia, Pennsylvania
9:40 AM - 10:00 AM Invited Presentation: Vascular Endothelial Endotypes in Sepsis, Eric Schmidt, MD, Massachusetts General Hospital, Boston, Massachusetts
10:00 AM - 10:10 AM Abstract Presentation: Defining Thrombocytopenia-Associated Multiple Organ Failure in the Plasma Proteome (4291288) 
10:10 AM - 10:20 AM Abstract Presentation: Machine Learning Prediction of Outcome in Pediatric Sepsis (4291824) 
10:20 AM - 10:30 AM Abstract Presentation: Evaluating Performance of the SepStratifier Algorithm in Pediatric Septic Shock (4294304) 
10:30 AM - 11:00 AM Refreshment Break
11:00 AM - 12:30 PM Parallel Session 4a: Immune and Cellular Dysfunction in Sepsis
Session Chair:
          Samithamby Jeyaseelan, DVM, PhD, Louisiana State University
11:00 AM - 11:20 AM Invited Presentation: Generation of Chronic Innate Exhaustion Memory and Long-term Disease Complications of Sepsis, Liwu Li, PhD, Virginia Tech University
11:20 AM - 11:40 AM Invited Presentation: Alcohol, Sepsis and Drunk Macrophages, Vidula Vachharanjani, MD, Cleveland Clinic, Cleveland, Ohio
11:40 AM - 12:00 PM Invited Presentation: Cellular Senescence in Sepsis, Raghavan Pillai Raju, PhD, Medical College of Georgia, Augusta, Georgia
12:00 PM - 12:10 PM Abstract Presentation: Interferon-Gamma Drives Harmful Hyperinflammatory Responses in a Murine Model of Sepsis (4281328) 
12:10 PM - 12:20 PM Abstract Presentation: Ethanol-Induced Changes in CD103 Expression and Function May Contribute to Immune Dysregulation in Sepsis (4282994) 
12:20 PM - 12:30 PM Abstract Presentation: A Novel IL1R2-ENO1 Interaction Inhibits Glycolysis-Mediated Pyroptosis and Protects Against Lethal Sepsis (4294522) 
11:00 AM - 12:30 PM Parallel Session 4b: Endotheliopathy Mechanisms and Resuscitating the Endothelium
Session Chairs:
          Kalev Freeman, MD, PhD, University of Vermont
          Jessica C. Cardenas, PhD, Universtiy of Colorado
11:00 AM - 11:20 AM Invited Presentation: Defining the Endotheliopathy of Hemorrhagic Shock and Trauma with an Eye on the Acute Response of the Epithelium to Injury, Alison B. Nair, MD, University of California San Francisco
11:20 AM - 11:40 AM Invited Presentation: Current Model of SHINE Endotheliopathy Driving Progressive Organ Failure, Mortality and Therapeutic Strategies, Kalev Freeman, MD, PhD, University of Vermont
11:40 AM - 12:00 PM Invited Presentation: Emerging Role of Endothelial Metabolism in Endotheliopathy and Coagulopathy of Trauma, Olan Jackson-Weaver, PhD, Tulane School of Medicine, New Orleans, Louisiana
12:00 PM - 12:10 PM Abstract Presentation: Conformational Activation of Von Willebrand Factor Mediates the Endotheliopathy of Trauma in Hemorrhagic Shock Patients (4292006) 
12:10 PM - 12:20 PM Abstract Presentation: Distinct Patterns of Rapid Extracellular Vesicle Release and Fast Plasma Membrane Movement in Endothelial Cells are Produced by Histone Exposure (4294480) 
12:20 PM - 12:30 PM Abstract Presentation: Hyaluronin-CD44 Signalling in Trauma-Induced Coagulopathy (4294535) 
12:30 PM - 1:30 PM Boxed Lunch
12:30 PM - 1:30 PM Value of Diversity in Medical Education and Shock Research
Session Chairs:
          Wendy Walker, PhD, Mercer University, Georgia
          Myung S. Park, MD, MS, Rochester, Minnesota
Invited Presentation: Value of Diversity in Medical Education, Priya Sinha Garg, MD, Boston University, Massachusetts
1:30 PM - 2:30 PM Update on DoD and NIH Funding
Session Chair:
          Scott C. Brakenridge, MD, Universtiy of Washington
1:30 PM - 1:50 PM Invited Presentation: Priorities and Opportunities in NIGMS Funding Programs, Rochelle Long, PhD, National Institute of General Medical Sciences, Bethesda, Maryland
1:50 PM - 2:30 PM Panel Session: Scientific Funding Challenges and Strategies, Timothy R. Billiar, MD, University of Pittsburgh; Laurie Kilpatrick, PhD, Temple University, Philadelphia, Pennsylvania; Rochelle Long, PhD, National Institute of General Medical Sciences, Bethesda, Maryland; Adam Gerber, MD, PhD, Octapharma USA, Paramus, New Jersey; Others to be Announced 
2:30 PM - 3:00 PM Refreshment Break
3:00 PM - 5:00 PM Plenary Session 5:  Everything Extracorporeal: A Translational Look at ECMO
Session Chairs:
          Linda Sousse, PhD, Institute for Extracorporeal Life Support, San Antonio, Texas
          Jared Gallaher, MD,MPH, University of North Carolina, Chapel Hill, North Carolina
3:00 PM - 3:20 PM Invited Presentation: ECMO Growth and Challenges: Patient Selection and Access, David Furfaro, MD, Harvard University, Boston, MA
3:20 PM - 3:40 PM Invited Presentation: Optimizing Access to and Delivery of ECMO: Building the Real Bridges, Anna Condella, MD, University of Washington, Seattle, WA
3:40 PM - 4:00 PM Invited Presentation: The Use of AI in ECMO and Extracorporeal Therapies, Linda Sousse, PhD, Institute for Extracorporeal Life Support, San Antonio, Texas
4:00 PM - 4:20 PM Invited Presentation: The Bleeding Edge: ECMO and Anticoagulation in Trauma, Jared Gallaher, MD, University of North Carolina, Chapel Hill, North Carolina
4:20 PM - 4:40 PM Invited Presentation: Use of VA ECMO in Severe Environmental Hypothermia, Sydney Hansen, MD, University of Minnesota, Minneapolis
4:40 PM - 4:50 PM Abstract Presentation: A Novel Multi-DAMP Scavenger OP18 Attenuates Gut Ischemia/Reperfusion-Induced Lung Injury (4286876) 
4:50 PM - 5:00 PM Abstract Presentation: Oncostatin-M Drives Capillary Leak In Critically Ill Via Novel JAK1/JNK/AP-1 Signalling and Junction Remodelling (4290344) 
6:00 PM - 6:30 PM Cocktail Reception
6:30 PM - 9:00 PM Dinner and Awards Banquet
Brief Remarks: 48th Annual Conference on Shock Thank You and Closing Remarks, Anthony E. Pusateri, PhD, 59th Medical Wing, Lackland Air Force Base, San Antonio, Texas, Shock Society Scientific Program Chair (2025)

Awards Presentation Chairs:
          Lauren T. Moffatt, PhD, Medstar Health Research Institute, Washington, DC
          Monowar Aziz, PhD, Feinstein Institutes for Medical Research, Northwell Health

Awards Presentations: Awardees to be announced